ABSTRACT
Purpose: To evaluate the surgical outcome of precision pulse capsulotomy (PPC) in phacoemulsification surgery. Methods: One hundred twenty-three eyes of 99 consecutive patients who underwent phacoemulsification with PPC through a 2.8 mm clear corneal incision were prospectively studied at a tertiary care centre. The size, shape of capsulotomy and intraoperative capsulotomy, and surgery-related complications were noted. Visual outcome, IOL stability, and signs of capsular opacification/contraction were evaluated at 3 and 6 months. Results: The mean age of patients was 49.5 ± 7.77 years. Complete, circular capsulotomy averaging 5.5 mm diameter was achieved in 117 of 123 eyes. In seven eyes, we experienced complications like capsulorhexis tear (n = 6) and inadvertent iris capture (n = 1). Probe malfunction occurred in six cases. Stable intracapsular intraocular lens (IOLs) fixation and centration was achieved in all eyes. None of the eyes had any significant posterior capsular opacification or capsular contraction at 3 and 6 months. In one eye anterior capsular opacification at the capsulotomy edge was noted at 6 months. Conclusion: PPC is a useful device for achieving a perfectly round capsulorrhexis. However, it has a learning curve and chances of skip areas in capsulorhexis, capsular tag, and its extension should be kept in mind. Special care should be taken in initial cases and while operating on eyes with poorly dilating pupil and mature cataracts.
ABSTRACT
Introduction: Breast carcinoma is the most common malignancy and the leading cause of death in women. Fine needle aspiration cytology (FNAC) plays a critical role in early diagnosis of any palpable breast lump. Aim and objectives: The aim of the study was to find out the utility of grading malignant breast tumours using Robinson’s cytology grading on FNAC and correlating it with Modified Bloom Richardson grading along with lymph node status assessment post-operatively by histopathological examination. Materials and methods: A retrospective study was conducted; cytological smears of 30 cases of breast carcinomas on FNAC were graded according to the Robinson’s cytology grading and correlated with Modified Bloom Richardson histopathological grading system over a period of 1 year. Results: There were a total of 28 (93.33%) cases of invasive ductal carcinoma, 1 case of mucinous carcinoma and 1 case of Metaplastic carcinoma. All patients were females with a mean age of 52.8 years. The correlation showed 85.71% concordance between the two grading systems with a 93.33% agreement and an observed weighted Kappa value of 0.916 implying a substantial strength of agreement. Chi-square statistical test performed for lymph node metastasis with grade of the tumor was statistically significant with a p-value of 0.0189 (p<0.05). Agarwal AA, Tambekar MY, Dhar R. Fine Needle Aspiration Cytology of Breast Carcinoma: A Comparative Study between Cytological and Histopathological Grading System with Lymph Node Status Assessment. IAIM, 2016; 3(10): 27-35. Page 28 Conclusion: Cytological grading of malignant breast carcinoma aspirates will help in the management and planning future treatment including preoperative neoadjuvant chemotherapy. We recommend it to be followed by all cytopathologists, in order to bring uniformity in the reporting of breast FNAs for grading the malignant lesions.